The Chicago White Sox are a Major League Baseball team based in Chicago, Illinois. The White Sox play in the American League's Central Division. Since 1991, the White Sox have played in U.S. Cellular Field, which was originally called New Comiskey Park and nicknamed The Cell by local fans. The White Sox are one of two major league clubs based in Chicago, the other being the Chicago Cubs of the National League. The White Sox last won the World Series in 2005 when they played the Houston Astros and swept them in four games.

One of the American League's eight charter franchises, the Chicago team was established as a major league baseball club in 1901. The club was originally called the Chicago White Stockings, after the nickname abandoned by the Cubs, and the name was soon shortened to Chicago White Sox, believed to have been because the paper would shorten it to Sox in the headlines. At this time, the team played their home games at South Side Park. In 1910, the team moved into historic Comiskey Park, which they would inhabit for more than eight decades.

The Chicago White Sox are most prominently nicknamed "the South Siders", differentiating them from the North Side Chicago Cubs. Other nicknames include "the Pale Hose", "the ChiSox", a combination of "Chicago" and "Sox" (as opposed to the BoSox), mostly just used by the national media, "the Go-Go Sox", a reference to 1959 AL champions, who got that nickname; "the Good Guys", a reference to the team's one-time motto "Good guys wear black", coined by Ken "Hawk" Harrelson; and "the Black Sox," the name attributed to the scandal-tainted 1919 team. Most fans refer to the team as simply "the Sox". The Spanish language media sometimes refer to the team as Medias Blancas for "White Stockings."

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